How to treat psoriasis. Kapcsolódó fájlok:

The PRESTA Psoriasis Randomized Etanercept STudy in Patients with Psoriatic Arthritis study, a randomized, double-blind, two-dose trial, examined the efficacy of etanercept treatment in patients with moderate-to-severe plaque psoriasis and PsA and the main results have been presented previously.
This analysis examined employment status, job duties and sick days, pre-defined endpoints in PRESTA, among this patient population.

All participants then received open-label etanercept 50 mg QW for 12 additional weeks, while remaining blinded to the randomization. A pharmacoeconomic questionnaire was administered at baseline, week 12 and week 24 of treatment.
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The questionnaire included employment status and changing job responsibilities and sick time taken due to psoriasis or PsA. The statistical methods included analysis of covariance, t-test, Fisher's exact test and McNemar's test.
Last-observation-carried-forward imputation was used for missing data. The number of monthly sick days also decreased from baseline to week 24 2.
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No significant differences between the treatment groups were observed for any economic endpoint at any time point. Effective treatment of psoriasis and PsA may reduce missed work days.